Guided by Experts
Online Hormone Replacement Therapy for Women
Is hormone imbalance stealing your joy?
You don’t have to suffer from hormone deficiency symptoms in silence. Defy Medical offers expertly guided online Hormone Replacement Therapy. This treatment utilizes bioidentical hormones to replenishes levels, so you can get back to enjoying life.
Get Started

Online Hormone Replacement Therapy patients report positive outcomes like:
- A renewed passion for life
- Healthy sex drive
- Better moods
- Relief from hot flashes and night sweats
- Improved body composition and an easier time reaching fat loss goals
- Less hormone-related anxiety and depression
- Decreased pain and/or discomfort during intercourse
“
"I thought menopause was the only reason for hormone imbalance."
”
Menopause is a main cause of hormone imbalance, but there are other reasons.
These include perimenopause, certain medications and medical conditions, surgeries like a hysterectomy and/or oophorectomy, and more.
If you’re not feeling as good as you used to, it’s worth checking your levels – no matter your age.
Are you a candidate for online Hormone Replacement Therapy?
Take our 3-minute quiz to see if you’re a potential candidate for hormone therapy.
Take the Quiz

Most women need multiple hormones to feel their best.
Symptoms and comprehensive blood testing help our providers determine which hormones you require.
Estrogen supports sexual and reproductive health. Online Hormone Replacement Therapy typically includes one of two forms: Estradiol or Estriol.
This hormone is responsible for regulating ovulation and menstruation and is often an essential part of a BHRT protocol.
While it’s considered a male hormone, women need Testosterone too! It supports sexual health, desire, and more.
This androgen is key to the creation of other hormones, including Estrogen and Testosterone.
Pregnenolone is a precursor hormone to Estrogen, Progesterone, Testosterone, and Cortisol.
HRT Treatment Options
Defy Medical creates an individualized plan based on your goals, comfort level, and blood test results. There are many options available to you depending on your needs.
Injectable BHRT
Hormone injections allow for careful control and quick adjustment of hormone levels.
Topical BHRT
Hormones can be absorbed through the skin using topical lotions and gels.
BHRT Capsules
These oral capsules deliver hormones in pill form.
BHRT Pellet Therapy
Pellets are implanted under the skin to deliver a steady dose of hormones over time.
BHRT Suppositories
Vaginal suppositories often help with vaginal dryness and discomfort.
“Kensie was thorough”
Visited on July 24, 2026
Kensie was thorough, professional and knowledgeable
–Gilda Rodriguez
“Michelle my NP was fantastic”
Visited on July 23, 2026
Michelle my NP was fantastic. She was very knowledgeable, patient and listened to my concerns. She address some key issues for me and created a plan that we will see if it works.
–JOHNSON,MARGARITA
“I felt heard with my symptoms by the…”
Visited on July 23, 2026
I felt heard with my symptoms by the nurse. She recognized my issue and is addressing my problem.
–Steffani James
“My First Experience w/Defy”
Visited on July 23, 2026
Dr. Calkins is personable and very informative. He makes sure the patient understands how the prescriptions could affect them and how to take them properly.
–GODDARD,CHRISTOPHER
“Fantastic guy easy chill relatable”
Visited on July 24, 2026
Fantastic guy easy chill relatable
–Eric Tomlinson
“Robin was very comprehensive and…”
Visited on July 24, 2026
Robin was very comprehensive and provided me with specific guidance, she was thorough & knowledgeable. It was a productive appointment.
–BT
“He listened and was understanding!!”
Visited on July 26, 2026
He listened and was understanding!!
–FOLDS,JESSICA
“She was so professional”
Visited on July 26, 2026
She was so professional, thorough, and smart.
–K Campton
“My experience with Defy over the last 9…”
Visited on July 26, 2026
My experience with Defy over the last 9 months has been great. They are quick to respond to any of my questions and always very informative. They pay attention to details and are always there when I need them. Everyone I’ve been in contact with has been a delight!
–Heaven P
“I can get what I want without leaving…”
Visited on July 25, 2026
I can get what I want without leaving my desk.
–SCARLETT,KIMBERLY
Showing our most recent 4- & 5-star reviews.
See All 3973 Reviews on
No more struggling to find a provider who listens and provides solutions.
Defy Medical: Your Women’s Health Experts
For more than a decade, Defy Medical has offered Bioidentical Hormone Replacement Therapy online. Led by Medical Director Dr. Justin Saya, our experienced care team has guided thousands of patients to living happier, healthier lives – and we’re ready to help you.
With Defy Medical, you access:
Expert Care
Our providers specialize in Women’s Health and use the latest advancements in BHRT.
Convenient Telemedicine
Access virtual consultations and simple online ordering of medications.
No Subscriptions or Contracts
You control your schedule and cost decisions, and only pay for what you need.
Extended 1-Hour Consults
You can ask questions, discuss your most pressing symptoms, and be heard by your provider.
Individualized Care Plans
We go deeper to get to the root causes and create a protocol as unique as you are.
Regular Follow-Up for Optimization
We don’t leave you on your own. Tracking your progress is key to optimizing hormone levels over time.
Simple Pharmacy Ordering
Conveniently order prescriptions, supplements, and supplies through our online patient portal for direct-to-door delivery.
A Variety of Health Services
We also offer sexual health treatments, injectable nutrition, Primary Care, and more.

More Services
You May Also Be Interested In:

Menopause Treatment
Menopause and perimenopause cause many changes to the body. You may experience shifts in your skin, hair, body composition, mood, libido, and more. Address the effects of menopause to feel better.

Female Sexual Dysfunction
Address Female Sexual Dysfunction (FSD) with therapies designed to improve libido, enhance sensation, and ease pain during intimacy.