Guided by Experts
Online Hormone Replacement Therapy for Women
Is hormone imbalance stealing your joy?
You don’t have to suffer from hormone deficiency symptoms in silence. Defy Medical offers expertly guided online Hormone Replacement Therapy. This treatment utilizes bioidentical hormones to replenishes levels, so you can get back to enjoying life.
Get Started

Online Hormone Replacement Therapy patients report positive outcomes like:
- A renewed passion for life
- Healthy sex drive
- Better moods
- Relief from hot flashes and night sweats
- Improved body composition and an easier time reaching fat loss goals
- Less hormone-related anxiety and depression
- Decreased pain and/or discomfort during intercourse
“
"I thought menopause was the only reason for hormone imbalance."
”
Menopause is a main cause of hormone imbalance, but there are other reasons.
These include perimenopause, certain medications and medical conditions, surgeries like a hysterectomy and/or oophorectomy, and more.
If you’re not feeling as good as you used to, it’s worth checking your levels – no matter your age.
Are you a candidate for online Hormone Replacement Therapy?
Take our 3-minute quiz to see if you’re a potential candidate for hormone therapy.
Take the Quiz

Most women need multiple hormones to feel their best.
Symptoms and comprehensive blood testing help our providers determine which hormones you require.
Estrogen supports sexual and reproductive health. Online Hormone Replacement Therapy typically includes one of two forms: Estradiol or Estriol.
This hormone is responsible for regulating ovulation and menstruation and is often an essential part of a BHRT protocol.
While it’s considered a male hormone, women need Testosterone too! It supports sexual health, desire, and more.
This androgen is key to the creation of other hormones, including Estrogen and Testosterone.
Pregnenolone is a precursor hormone to Estrogen, Progesterone, Testosterone, and Cortisol.
HRT Treatment Options
Defy Medical creates an individualized plan based on your goals, comfort level, and blood test results. There are many options available to you depending on your needs.
Injectable BHRT
Hormone injections allow for careful control and quick adjustment of hormone levels.
Topical BHRT
Hormones can be absorbed through the skin using topical lotions and gels.
BHRT Capsules
These oral capsules deliver hormones in pill form.
BHRT Pellet Therapy
Pellets are implanted under the skin to deliver a steady dose of hormones over time.
BHRT Suppositories
Vaginal suppositories often help with vaginal dryness and discomfort.
“The provider was attentive and let me…”
Visited on August 13, 2026
The provider was attentive and let me explain my entire situation, which led to a much better outcome.
–KRAMER,ELLEN
“Great consultation”
Visited on August 13, 2026
I enjoyed talking with Beth she explained everything to me with my lab results and we have a plan to get started on my road to feeling better.
–Jb
“He was very knowledgeable and answered…”
Visited on August 13, 2026
He was very knowledgeable and answered any questions that I had.
–JONES,SPENCER
“Thanks for the consultation”
Visited on August 13, 2026
Thanks for the consultation. Very professional and detailed.
–WOOTTEN,SHAWN
“Ben Walker gets it”
Visited on August 15, 2026
Ben Walker gets it
–Noob
“Dr Calkins listened”
Visited on August 15, 2026
Dr Calkins listened, was knowledgeable, and did a great job remembering what we discussed. He seems great. Defy, however, takes way too long to send prescriptions and lab orders. Midi had them sent to me within an hour of my visit.
–GILLRIE,STEFFANIE
“Very personal and informative”
Visited on August 14, 2026
Very informative and helpful answers all my questions
–FORSYTH,JULIET
“Follow up”
Visited on August 14, 2026
Mike is always knowledgeable and thank to Defy for making this possible.
–ASADZIAN,IVAN
“She was very professional & explained…”
Visited on August 14, 2026
She was very professional & explained everything in detail. Very compassionate because I lost my grandson who was 18 in a fatality accident.
Went over all my labs thoroughly..
–MCGLOTHLIN,DENISE
“So far good experience with the doc”
Visited on August 15, 2026
So far good experience with the doc. Very thorough and answered all my questions
–PEARSALL,GARRETT
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No more struggling to find a provider who listens and provides solutions.
Defy Medical: Your Women’s Health Experts
For more than a decade, Defy Medical has offered Bioidentical Hormone Replacement Therapy online. Led by Medical Director Dr. Justin Saya, our experienced care team has guided thousands of patients to living happier, healthier lives – and we’re ready to help you.
With Defy Medical, you access:
Expert Care
Our providers specialize in Women’s Health and use the latest advancements in BHRT.
Convenient Telemedicine
Access virtual consultations and simple online ordering of medications.
No Subscriptions or Contracts
You control your schedule and cost decisions, and only pay for what you need.
Extended 1-Hour Consults
You can ask questions, discuss your most pressing symptoms, and be heard by your provider.
Individualized Care Plans
We go deeper to get to the root causes and create a protocol as unique as you are.
Regular Follow-Up for Optimization
We don’t leave you on your own. Tracking your progress is key to optimizing hormone levels over time.
Simple Pharmacy Ordering
Conveniently order prescriptions, supplements, and supplies through our online patient portal for direct-to-door delivery.
A Variety of Health Services
We also offer sexual health treatments, injectable nutrition, Primary Care, and more.

More Services
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Menopause Treatment
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Address Female Sexual Dysfunction (FSD) with therapies designed to improve libido, enhance sensation, and ease pain during intimacy.