Find the root cause of your symptoms with Defy Medical.
"Why do I feel this way?"
Feeling a decline in drive, energy, and libido? Defy Medical uses in-depth consultations, comprehensive blood testing, and a decade of experience to develop customized treatments via telemedicine.
Feel better. Defy expectations.
Defy Medical
The World’s Leading Hormone Replacement Clinic
Defy Medical has guided thousands of patients to living healthier, happier lives – and we’re ready to help you. Our experienced care team specializes in hormone restoration and integrative therapies designed to help you feel better.
Get Started
Wondering if HRT is right for you?
Take our 3-minute quiz to see if you may be a candidate for Hormone Replacement Therapy.
This quiz is meant to provide guidance and is not intended to be medical advice. Blood testing and consulting with a knowledgeable provider are required to diagnose hormone deficiency.
Take the Quiz
Some of Our
Core Services
For Men
Testosterone Replacement Therapy
Optimize your levels and performance with a customized treatment plan for low Testosterone (hypogonadism).
Erectile Dysfunction
Regain satisfaction with your sex life and enhance your sexual performance. Find effective and affordable therapies for erectile dysfunction.
For Women
Hormone Therapy
Combat the effects of hormone imbalance and regain your zest for life with Bioidentical Hormone Replacement Therapy (BHRT).
Sexual Dysfunction
Enhance intimacy with treatments designed to boost libido, improve sensation, and ease pain during intercourse.
Meet our Care Team
Led by Medical Director Dr. Justin Saya, our care team has extensive experience in hormone restoration, sexual health treatment, and integrative wellness. They’re passionate about helping patients improve their lives and feel their best.
See Our ProvidersWhat Our Patients are Saying
Showing our most recent 4- & 5-star reviews.
See All 3763 Reviews on
“Thankful for Dr Saya and his team”
Visited on September 5, 2025
Dr Saya is knowledgeable regarding hormone therapy and very thorough. He is very kind and easy to talk to. I feel so much better since he has regulated my thyroid and sex hormones. All of my labs have improved dramatically. My PCP and my cardiologist are both impressed with my improved health.
–DEBORAH
“Very positive experience!”
Visited on September 3, 2025
Megan was very informative and helpful! I appreciated the options presented to me for HRT. She was very personable !
–SHIRLEY
“Dr. Caulkins”
Visited on September 4, 2025
Dr. Caulkins was extremely easy to discuss all issues with and explain everything discussed so it was easily understandable.
–Mariah Megarry
“Good experience as usual”
Visited on September 4, 2025
My provider is always thorough with her questions and takes time to listen to my concerns
–KAREN ZAWADZKI
“تعامل جداً لبق”
Visited on September 5, 2025
تجربة ممتازة
–كابريلا الياس
“Morgan was great”
Visited on September 3, 2025
Morgan was great. Very knowledgeable and thorough. So far every interaction I’ve had with someone at Defy has been great.
–MIRA
“Dr. Calkins”
Visited on September 2, 2025
Easy to talk and relate to. I felt like Dr. Calkins really cared about me during our time together.
–ARTHUR GLINKIN
“Ben is extremely smart and…”
Visited on July 9, 2025
Ben is extremely smart and knowledgeable
He always answers all questions accurately
Ben has changed my life. Because of Ben and the medications he helped me with I feel the best I have felt in more than 12 years
Increased stamina, strength, very good mood all the time, increased cognitive function. Ben is a life changer.
–ALEXANDER LIPWORTH
“My new provider Michael’s extraordinary…”
Visited on August 31, 2025
My new provider Michael’s extraordinary knowledge, understanding, and expert advice is an experience I haven’t gotten from other clinics. I feel like I’m finally in good hands now.
–ZACHARY CHASSE
“Attentive and thorough”
Visited on August 28, 2025
She listens and really takes in everything I have to say. She helps find solutions that are within my budget. I love her approach to the “just because its normal doesn’t mean its normal”
–Valued Customer
News and Health Articles
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