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Platelet-Rich Plasma (PRP)
Hair Restoration Injections for Men and Women

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Hair Restoration Injections

The root cause of hair loss in men and women
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Male and female pattern baldness, also known as Androgenic Alopecia, is the most common cause of hair loss and can affect up to 70% of men and 40% of women at some point in their lifetime. Men typically show this with hairline recession at the temples and hair-loss on the upper surface of the head, also known as vertex balding.Women typically show this with scattered thinning throughout the scalp or thinning of the hair over the top of their scalp.

People who suffer from this type of hair-loss have an underlying sensitivity to hair follicle miniaturization due to androgenic hormones. Miniaturization refers to the shrinking of the hair follicle. This shrinking results in thinning or loss of hair. Dihydrotestosterone (DHT) is the primary hormone associated with the miniaturization of hair follicles. DHT is a by-product of the hormone testosterone. Testosterone, which is found in both men and women, converts naturally to DHT through a hormonal pathway called 5 Alpha Reductase. Certain hairs on your head may be genetically susceptible to thin if exposed to excess levels of DHT. This DHT can attach to the hair follicle and cause it to prematurely shed while shrinking the follicle and preventing normal hair re-growth. Instead of normal, healthy hair growing in its place, a thinner, finer hair replaces it.

According to the Foundation for Hair Restoration, the onset of miniaturization from androgenic alopecia is due to three factors:

1. Genetic predisposition

2. Presence of Dihydrotestosterone (DHT)

3. Age

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Common causes of hair loss

More than 95% of hair-loss in men is due to this condition. This type of hair loss also affects women.

Studies show that limited food intake and deficiencies in certain nutrients can cause thinning. These include deficiencies of biotin, amino-acids (protein), zinc and iron. Consuming a diet high in animal fat, such as found in fast food, can also result in hair loss.

Stress has been shown to restrict the blood supply to the capillaries. This restriction prevents hair growth by cutting off oxygen and nutrients to the hair follicle. This effect is similar to having poor circulation.

Some medications can cause hair loss, especially medications that affect hormone levels. These medications include contraceptive pills, some forms of hormone replacement therapy, anabolic steroids, and acne medication. Other medications that can have an effect on hair loss include those designed to treat blood pressure, diabetes, heart disease, and cholesterol.

Platelet-Rich Plasma Injections for Hair Restoration
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We provide Platelet-Rich Plasma (PRP) injections as part of an integrative approach to restore and prevent further loss of your hair. PRP therapy has established itself to be effective as a medical treatment modality in the specialty fields of oral surgery, neurosurgery, plastic and cosmetic surgery, sports medicine and orthopedics. It has been used extensively in these specialties with generally positive outcomes and success. In the field of hair restoration, evidence supports PRP therapy as a promising treatment option to promote hair growth.

How Does PRP Work?

Platelet-Rich Plasma (PRP) is a concentrated blood sample that contains high levels of platelets, a critical component of the wound healing process. Platelets contain growth factors that are responsible for soft tissue repair, bone regeneration, development of new blood vessels, and stimulation of the wound healing process. Inside the Platelets are many intracellular structures such as glycogen, lysosomes and alpha granules. These granules within the PRP contain clotting and growth factors that are eventually released during the healing and repair process. Platelets can theoretically cause growth of the hair follicles by stimulating the stem cells and other cells in the microenvironment of the hair follicle. The primary purpose of using PRP in hair restoration is to stimulate inactive or newly implanted hair follicles into an active growth phase.

See recent research that shows the effectiveness of PRP for hair loss.

PRP Specific Growth Factors that Influence Hair Growth

Platelet-Derived Growth Factor (PDGF): Promotes blood vessel growth, cell replication, and skin formation

Transforming Growth-Factor-Beta (TGF-b): Promotes growth of matrix between cells

Vascular Endothelial Growth Factor (VEGF): Promotes blood vessel formation

Epidermal Growth Factor (EGF): Promotes cell growth and differentiation, blood vessel formation, collagen formation

Fibroblast Growth Factor-2 (FGF-2): Promotes growth of specialized cells and blood vessel formation

Insulin Like Growth Factor (IGF): Acts as a regulator of normal physiology in nearly every type of cell in the body

Terumo Harvest® SmartPrep® System

This system is considered as the gold standard in PRP and Stem Cell harvest technology. With its patented Cell Capture™ Technology, the Harvest® SmartPrep® System consistently delivers the optimal cellular composition and concentration of autologous platelet product to optimize conditions for healing and restoration.

icon platelets
Recovers the highest percentage of platelets and corresponding growth factors – up to 80% of available platelets
icon stem cells v2
Contains increased concentrations of stem cells
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Reduces the granulocyte levels to deliver a non-inflammatory product
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Generates the greatest level of reproducibility – only 5% coefficient of variance
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Only 15 minutes processing time for the highest quality PRP

 

In addition, the Harvest system has documented sterility of concentrated platelet product when following the manufacturer’s instructions for use. It also delivers a concentration of autologous platelets and growth factors that is roughly 4-6 times greater than that found in whole blood. Unlike other products, it delivers a broad range of growth factors in the proper concentration and ratios to help optimize conditions for healing. Clinical studies have shown that application of PRP can help reduce bleeding, minimize pain, reduce infection rates, and optimize overall healing. Harvest is a leader in products used to process and concentrate platelets, bone marrow aspirate, and adipose tissue.

The PRP Hair Restoration Process
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Initial Laboratory Tests

We will require a few lab tests prior to your first treatment. The purpose is to provide a review of your overall health in addition to blood characteristics including platelet count prior to receiving PRP treatment. The tests included in this panel will also detect common hormonal causes of pattern baldness in both men and women. The information gathered from these tests will allow our medical team to customize a hair restoration treatment specific for each patient. All tests are included with the initial treatment.

Tests include:

• Testosterone Free & Total

• Dihydrotestosterone (DHT)

• Estradiol (Estrogen E2)

• Complete Blood Count (CBC)

• Comprehensive Metabolic Panel

• Thyroid Stimulating Hormone (TSH)

Steps of the PRP Hair Restoration Process

 

Step 1 Harvest: A nurse will perform your phlebotomy (blood draw). A specific amount of blood will be drawn depending on the amount of PRP needed for your treatment.

Step 2 Separate Platelet Concentration: Immediately following the blood draw, your blood will be processed to recover the highest percentage of platelets with corresponding growth factors and high concentration of stem cells.

Step 3 Activate: PRP is activated.

Step 4 Platelet Injection: A topical numbing block will be applied to the top of your head to eliminate any pain during the procedure. Additional anesthetic is available by injection for complete numbing. At this time, the doctor will inject the Platelet Rich Plasma (PRP) at specific intervals and depth to ensure the entire treatment area has been thoroughly exposed to the PRP.

Common Questions and Concerns about PRP Hair Restoration

PRP has been used successfully in other medical and surgical disciplines for many years. The decision to use PRP is a personal decision and should be made after careful research, consideration, and consultation with a physician. PRP is safe and natural because the procedure concentrates the good cells from your own blood and injects them directly back into the area where it is needed. PRP is immunologically neutral and poses no danger of allergic, hypersensitivity, or foreign-body reactions.

In the medical treatment of male and female pattern baldness (androgenetic alopecia), PRP can be injected into the balding scalp to potentially stimulate thin (miniaturized) hair to grow into thicker (terminal) hairs. Patients with thinning, but not totally bald, areas would be the best candidates.

Patients with a history of heavy smoking, drug or alcohol use may not be good candidates for this treatment. Patients who have been diagnosed with the following medical conditions may not be good candidates for this PRP treatment: platelet dysfunction syndromes, thrombocytopenia, hypofibrinogenaemia, hemodynamic instability, sepsis, acute and chronic infections, chronic liver disease, anticoagulation therapy, chronic skin diseases or cancer, metabolic and systemic disorders. If the hair follicles are entirely lost, the treatment will not work. Patients who have lost their hair follicles require hair transplant surgery.

Patients may experience a brief period of inflammation at the application sites. Inflammation may be associated with release of platelet-associated factors at the application site. In addition, the scalp is usually tender for a few days after the procedure.

After the initial treatment, a second treatment is recommended at 4 weeks and then repeated every three months for the first year. After the first year, treatments are administered every 6-12 months depending upon your response.