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How much weight can I expect to lose with GLP-1 therapy?

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Weight loss results vary based on individual factors, and we cannot make guarantees about the amount of weight a patient may lose.

That said, studies do point to an average weight loss percentage:

  • 10-15% of body weight over 14 months with Semaglutide
  • 15-25% of body weight over 18 months with Tirzepatide

There are many factors that contribute to how much weight patients lose. These include:

  • Starting weight and BMI – People with more body fat may experience more substantial weight loss.
  • Adherence to medication schedule – It’s very important that patients stick to their dosage schedule to get the maximum benefit.
  • Diet and exercise habits – A healthy diet and regular exercise are crucial factors in GLP-1 weight loss plans.
  • Individual metabolic response – Metabolic health varies by patient and can significantly impact weight loss.
  • Dosage and duration of treatment – GLP-1 medications show their greatest benefit over time, so the duration of your weight loss treatment plays a factor in how much weight you’ll lose.

Your Defy Medical provider can help set realistic expectations based on your individual situation and help you maximize your results through comprehensive support.