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Find the root cause of your symptoms with Defy Medical.

"Why do I feel this way?"

Feeling a decline in drive, energy, and libido? Defy Medical uses in-depth consultations, comprehensive blood testing, and a decade of experience to develop customized treatments via telemedicine.

Feel better. Defy expectations.

Defy Medical

The World’s Leading Hormone Replacement Clinic

Defy Medical has guided thousands of patients to living healthier, happier lives – and we’re ready to help you. Our experienced care team specializes in hormone restoration and integrative therapies designed to help you feel better.

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Wondering if HRT is right for you?

Take our 3-minute quiz to see if you may be a candidate for Hormone Replacement Therapy.

This quiz is meant to provide guidance and is not intended to be medical advice. Blood testing and consulting with a knowledgeable provider are required to diagnose hormone deficiency.

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Some of Our

Core Services

For Men

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Testosterone Replacement Therapy

Optimize your levels and performance with a customized treatment plan for low Testosterone (hypogonadism).

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Erectile Dysfunction

Regain satisfaction with your sex life and enhance your sexual performance. Find effective and affordable therapies for erectile dysfunction.

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For Women

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Hormone Therapy

Combat the effects of hormone imbalance and regain your zest for life with Bioidentical Hormone Replacement Therapy (BHRT).

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Sexual Dysfunction

Enhance intimacy with treatments designed to boost libido, improve sensation, and ease pain during intercourse.

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Meet our Care Team

Led by Medical Director Dr. Justin Saya, our care team has extensive experience in hormone restoration, sexual health treatment, and integrative wellness. They’re passionate about helping patients improve their lives and feel their best.

See Our Providers

What Our Patients are Saying

Showing our most recent 4- & 5-star reviews.

TrustScore 5 out of 5 See All 2729 Reviews on Trustpilot

Read More Patient Stories

“Dr Calkins is very knowledgeable”

Visited on October 3, 2024

Dr Calkins is very knowledgeable, patient and answered all my questions. I am very pleased with my consultation and look forward for improvement in my health.

–ZHANNA T

5 out of 5

“Thorough”

Visited on October 4, 2024

Marisa provided a thorough analysis of my bloodwork and made several very good recommendations. Explained things with clear explanations and took the time to do so.

–Tom H.

5 out of 5

“Caleb was amazing!”

Visited on October 3, 2024

Caleb was amazing!! My case is a little complex due to some medical history. He explained more to me than any doctor I have seen in the past ten years. I couldn’t thank him enough.

–BONNIE CARROLL

5 out of 5

“This is top tier care”

Visited on October 1, 2024

This is top tier care, I couldn’t ask for better.
I would be very interested in having my TRT care switched from my current provider, to defy. I simply would need a total cost for treatment.

–FREDRICK WEST

5 out of 5

“Janel is always professional and caring.”

Visited on October 2, 2024

Janel is always professional and caring.

–MARGARET TIERNEY

5 out of 5

“Michael is a fantastic provider”

Visited on October 4, 2024

Michael is a fantastic provider. His constant research and personal experience with the care options gives him the credibility and insight I rely on for the best possible results.

–MORGAN PORTER

5 out of 5

“Beth is amazing.”

Visited on October 1, 2024

Beth is amazing. She is a truly gifted medical professional who really has the patient’s best at heart. I sincerely appreciate not only how knowledgeable and competent she is, but the empathy and kindness she shows us. Thanks for everything, you’ve made a huge difference in my quality of life.

–Nate R

5 out of 5

“Jill listened and understood”

Visited on October 1, 2024

Jill listened and understood my frustrations and health journey. I am hoping with her guidance that my quality of life will continue to improve.

–TERESA MCLAREN

5 out of 5

“Janel is an exceptional medical provider”

Visited on October 1, 2024

Janel is caring, personable and very knowledgable. The consultation didn’t feel awkward or rushed, it felt as if I was talking to an old friend. Her recommendations made sense and she reiterated multiple times that it’s ok for me to reach out if HRT protocol is giving me trouble. A genuine medical professional that is truly a needle in a haystack. We need more providers like her!

–AGNE SOLOMON

5 out of 5

“Attentive!”

Visited on October 1, 2024

He was attentive and listened to my health goals and concerns.

–GERARD RICHARDS

5 out of 5