Find the root cause of your symptoms with Defy Medical.
"Why do I feel this way?"
Feeling a decline in drive, energy, and libido? Defy Medical uses in-depth consultations, comprehensive blood testing, and a decade of experience to develop customized treatments via telemedicine.
Feel better. Defy expectations.
Defy Medical
The World’s Leading Hormone Replacement Clinic
Defy Medical has guided thousands of patients to living healthier, happier lives – and we’re ready to help you. Our experienced care team specializes in hormone restoration and integrative therapies designed to help you feel better.
Get Started
Wondering if HRT is right for you?
Take our 3-minute quiz to see if you may be a candidate for Hormone Replacement Therapy.
This quiz is meant to provide guidance and is not intended to be medical advice. Blood testing and consulting with a knowledgeable provider are required to diagnose hormone deficiency.
Take the Quiz
Some of Our
Core Services
For Men
Testosterone Replacement Therapy
Optimize your levels and performance with a customized treatment plan for low Testosterone (hypogonadism).
Erectile Dysfunction
Regain satisfaction with your sex life and enhance your sexual performance. Find effective and affordable therapies for erectile dysfunction.
For Women
Hormone Therapy
Combat the effects of hormone imbalance and regain your zest for life with Bioidentical Hormone Replacement Therapy (BHRT).
Sexual Dysfunction
Enhance intimacy with treatments designed to boost libido, improve sensation, and ease pain during intercourse.
Meet our Care Team
Led by Medical Director Dr. Justin Saya, our care team has extensive experience in hormone restoration, sexual health treatment, and integrative wellness. They’re passionate about helping patients improve their lives and feel their best.
See Our ProvidersWhat Our Patients are Saying
Showing our most recent 4- & 5-star reviews.
See All 3900 Reviews on
“Excellent consultation”
Visited on July 3, 2026
Excellent consultation
–Robert Fischer
“Megan was very knowledgeable”
Visited on July 3, 2026
Megan was very knowledgeable.
Defy could do a better job in notifications of due dates-for labs and medication refills.
–Timothy
“Ben was terrific”
Visited on July 2, 2026
Ben was terrific. It was nice working with someone that listens to patients concerns and addresses them. Highly recommend the team at Defy.
–Tim A
“Super Informative”
Visited on July 2, 2026
Super Informative! All my questions were entered, thoroughly. Great place!
–DIAZ,PETER
“thorough”
Visited on July 4, 2026
thorough, unhurried
–Michael Dyas
“Great Dr’s”
Visited on July 4, 2026
Every question I had was answered with an incredible amount of knowledge. Just like it should be.
–JAMES F
“Michael has a wide range of knowledge!”
Visited on July 4, 2026
Michael was extremely knowledgeable about thyroid function, hormone needs, and testosterone replacement. His understanding of my gene breaks and how they affect my overall functioning was very impressive! I woukd highly recommend working with him!
–Drumond,Julianna
“Ben was wonderful”
Visited on July 5, 2026
Ben was wonderful! He was extremely knowledgeable. He also listened and was patient. I didn’t feel rushed during the call which I appreciated. I am hopeful I will have a good experience with Defy moving forward
–Gina
“Great”
Visited on July 2, 2026
Easy and fast treatment
–SCHULTZ,CODY
“I always feel like Dr Calkins really…”
Visited on July 2, 2026
I always feel like Dr Calkins really listens to my concerns. I never feel rushed and he always has ideas or solutions.
–LAWSON,DENISE
News and Health Articles
Learn more about integrative therapies, hormone restoration, and more.
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GLP-1 agonists like Semaglutide impact blood sugar and support metabolic health. Recently, they've shown promise in helping with weight loss.
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What Changing USP Guidelines Mean for You
USP recently updated its guidelines around the production and shipment of medications. These updates change how pharmacies operate.
Learn More About What Changing USP Guidelines Mean for You