Find the root cause of your symptoms with Defy Medical.
"Why do I feel this way?"
Feeling a decline in drive, energy, and libido? Defy Medical uses in-depth consultations, comprehensive blood testing, and a decade of experience to develop customized treatments via telemedicine.
Feel better. Defy expectations.
Defy Medical
The World’s Leading Hormone Replacement Clinic
Defy Medical has guided thousands of patients to living healthier, happier lives – and we’re ready to help you. Our experienced care team specializes in hormone restoration and integrative therapies designed to help you feel better.
Get Started
Wondering if HRT is right for you?
Take our 3-minute quiz to see if you may be a candidate for Hormone Replacement Therapy.
This quiz is meant to provide guidance and is not intended to be medical advice. Blood testing and consulting with a knowledgeable provider are required to diagnose hormone deficiency.
Take the Quiz
Some of Our
Core Services
For Men
Testosterone Replacement Therapy
Optimize your levels and performance with a customized treatment plan for low Testosterone (hypogonadism).
Erectile Dysfunction
Regain satisfaction with your sex life and enhance your sexual performance. Find effective and affordable therapies for erectile dysfunction.
For Women
Hormone Therapy
Combat the effects of hormone imbalance and regain your zest for life with Bioidentical Hormone Replacement Therapy (BHRT).
Sexual Dysfunction
Enhance intimacy with treatments designed to boost libido, improve sensation, and ease pain during intercourse.
Meet our Care Team
Led by Medical Director Dr. Justin Saya, our care team has extensive experience in hormone restoration, sexual health treatment, and integrative wellness. They’re passionate about helping patients improve their lives and feel their best.
See Our ProvidersWhat Our Patients are Saying
View All Testimonials“Working with Defy has been the best decision I've ever made...”
Dr. Saya and team have been a godsend for me. Other doctors have brushed me off, saying my labs were in ‘normal’ range, but never listened to the symptoms I was suffering from. Working with Defy has been the best decision I’ve ever made, and I’ll continue to recommend them to others.
–Mike
“I no longer have the hot flashes (YES!), and my moods are even...”
[My husband and I] have been seeing Dr. Saya, and now Jill, for several years now. I even switched my thyroid care to them as well. I no longer have the hot flashes (YES!), and my moods are even, no extreme mood swings. Thank goodness!
–Kimberly
“I want to thank Dr. Calkins from the bottom of my heart.”
No doctor in my town wanted to treat me because I was only 25, despite having diagnosis, imaging and bloodwork indicating I needed the help. I want to thank Dr. Calkins from the bottom of my heart. The past few months have been so liberating for me and I finally feel in control of my life. Also, for the first time in my life, I can truly say I’m happy. I’m not just going through the motions to get through the day anymore.
–Alan
News and Health Articles
Learn more about integrative therapies, hormone restoration, and more.
The Complete Guide to TRT for Men
Testosterone Replacement Therapy (TRT) helps treat low Testosterone, or hypogonadism, in men.
Learn More About The Complete Guide to TRT for Men
Semaglutide For Weight Loss
Semaglutide has shown promise in treating chronic weight gain and obesity. Learn more about how Semaglutide for weight loss works.
Learn More About Semaglutide For Weight Loss
The Complete Guide to BHRT for Women
Hormone imbalance has many causes and leads to damaging symptoms. Our guide to BHRT for women covers the basics of this life-changing therapy.
Learn More About The Complete Guide to BHRT for Women