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Find the root cause of your symptoms with Defy Medical.

"Why do I feel this way?"

Feeling a decline in drive, energy, and libido? Defy Medical uses in-depth consultations, comprehensive blood testing, and a decade of experience to develop customized treatments via telemedicine.

Feel better. Defy expectations.

Defy Medical

The World’s Leading Hormone Replacement Clinic

Defy Medical has guided thousands of patients to living healthier, happier lives – and we’re ready to help you. Our experienced care team specializes in hormone restoration and integrative therapies designed to help you feel better.

Get Started

Wondering if HRT is right for you?

Take our 3-minute quiz to see if you may be a candidate for Hormone Replacement Therapy.

This quiz is meant to provide guidance and is not intended to be medical advice. Blood testing and consulting with a knowledgeable provider are required to diagnose hormone deficiency.

Take the Quiz

Some of Our

Core Services

For Men

Testosterone Replacement Therapy

Optimize your levels and performance with a customized treatment plan for low Testosterone (hypogonadism).

Learn More About Testosterone Replacement Therapy

Erectile Dysfunction

Regain satisfaction with your sex life and enhance your sexual performance. Find effective and affordable therapies for erectile dysfunction.

Learn More About Erectile Dysfunction

For Women

Hormone Therapy

Combat the effects of hormone imbalance and regain your zest for life with Bioidentical Hormone Replacement Therapy (BHRT).

Learn More About Hormone Therapy

Sexual Dysfunction

Enhance intimacy with treatments designed to boost libido, improve sensation, and ease pain during intercourse.

Learn More About Sexual Dysfunction

Meet our Care Team

Led by Medical Director Dr. Justin Saya, our care team has extensive experience in hormone restoration, sexual health treatment, and integrative wellness. They’re passionate about helping patients improve their lives and feel their best.

See Our Providers

What Our Patients are Saying

Showing our most recent 4- & 5-star reviews.

TrustScore 5 out of 5 See All 4038 Reviews on Trustpilot

Read More Patient Stories

“The provider was attentive and let me…”

Visited on August 13, 2026

The provider was attentive and let me explain my entire situation, which led to a much better outcome.

–KRAMER,ELLEN

5 out of 5

“Great consultation”

Visited on August 13, 2026

I enjoyed talking with Beth she explained everything to me with my lab results and we have a plan to get started on my road to feeling better.

–Jb

5 out of 5

“He was very knowledgeable and answered…”

Visited on August 13, 2026

He was very knowledgeable and answered any questions that I had.

–JONES,SPENCER

5 out of 5

“Thanks for the consultation”

Visited on August 13, 2026

Thanks for the consultation. Very professional and detailed.

–WOOTTEN,SHAWN

5 out of 5

“Ben Walker gets it”

Visited on August 15, 2026

Ben Walker gets it

–Noob

5 out of 5

“Dr Calkins listened”

Visited on August 15, 2026

Dr Calkins listened, was knowledgeable, and did a great job remembering what we discussed. He seems great. Defy, however, takes way too long to send prescriptions and lab orders. Midi had them sent to me within an hour of my visit.

–GILLRIE,STEFFANIE

5 out of 5

“Very personal and informative”

Visited on August 14, 2026

Very informative and helpful answers all my questions

–FORSYTH,JULIET

5 out of 5

“Follow up”

Visited on August 14, 2026

Mike is always knowledgeable and thank to Defy for making this possible.

–ASADZIAN,IVAN

5 out of 5

“She was very professional & explained…”

Visited on August 14, 2026

She was very professional & explained everything in detail. Very compassionate because I lost my grandson who was 18 in a fatality accident.
Went over all my labs thoroughly..

–MCGLOTHLIN,DENISE

5 out of 5

“So far good experience with the doc”

Visited on August 15, 2026

So far good experience with the doc. Very thorough and answered all my questions

–PEARSALL,GARRETT

5 out of 5