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Platelet-Rich Plasma (PRP)

Joint Related Issues

PRP Therapy Overview


PRP for Joint Related Issues

Benefits of PRP Therapy

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Packed with growth and healing factors, platelets initiate repair and attract the critical assistance of stem cells

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PRP’s natural healing process intensifies the body’s efforts by delivering a higher concentration of platelets directly into the area in need

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To create PRP, a small sample of your blood is drawn (similar to a lab test sample) and placed in a centrifuge that spins the blood at high speeds, separating the platelets from the other components. The process is handled manually by a lab technician, producing higher concentrations of platelets and a purer concentration of the beneficial blood components

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Because the patient’s own blood is used, there is no risk of a transmissible infection and a low risk of allergic reaction

Platelet-Rich Plasma Injections for Chronic Tendonitis

Platelet-Rich Plasma (PRP) Therapy is a non-surgical treatment which can reduce pain and provide long-term relief from common orthopedic conditions including osteoarthritis and chronic tendonitis. Athletes and active individuals of all ages who endure chronic pain from tendon injuries or osteoarthritis may finally get relief from this procedure. PRP utilizes platelets from the athletes' own blood to rebuild damaged tendons or cartilage. It has been successful not only relieving pain but also in promoting the healing process. The body’s first response to soft tissue injury is to deliver platelet cells to the damaged area, so this procedure aids that process.


Platelet Injections can help improve:
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Achilles Tendonitis
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Bicep Tendonitis
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Tennis Elbow
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Golf Elbow
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Patellar Tendonitis
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Platelet-Rich Plasma Injections for Osteoarthritis

Osteoarthritis, also known as degenerative arthritis or degenerative joint disease, is a group of ailments involving degradation of joints, including articular cartilage and subchondral bone. Symptoms may include joint pain, tenderness, stiffness, locking, and sometimes an effusion (an accumulation of fluid).

When bone surfaces become less well protected by cartilage, they may be exposed and damaged. Along with pain can come decreased movement, which can cause nearby muscles to atrophy and ligaments to become more lax.

PRP therapy is done in an exam room and takes less than an hour. The patient's blood is drawn and placed in a centrifuge for 15 minutes to separate out the platelets. The platelet-rich plasma is injected into the damaged portion of the tendon or cartilage. This concentrated injection of platelets and growth factors can help jumpstart healing in areas affected by Osteoarthritis.

Platelet-Rich Plasma Injections for Tendonitis

Tendons are the rope-like structures that connect muscle to bone, enabling the bone to move. When a tendon is first injured, it can become inflamed and swollen, resulting in pain. This injury is common with athletes and active individuals who engage in physical activity that requires repetitive motions. Athletes who endure chronic pain from tendon injuries can finally get relief from a safe, non-surgical procedure. This therapy has successfully treated patients at Defy by relieving pain and jump-starting the healing process.

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“I received a series of PRP injections in my left knee which had been injured over the years from sports and while in the military. I had significant atrophy in my left leg plus pain and weakness in the left knee but had never addressed the injury with surgery or any treatment until I tried PRP injections.
After the first PRP treatment, I followed up with a series of injections every 2-3 months and noticed significant improvement by the third session. I felt reduced pain, especially after exercise or intense running and hiking. I also felt more stability in general.
PRP injections have allowed me to continue living my life pain free – without needing surgery.”

–David, Defy Medical patient

Terumo Harvest® SmartPrep® System

The system used by Defy Medical is considered the gold standard in PRP and Stem Cell harvest technology. The Harvest® SmartPrep® System uses patented technology to deliver optimal results for healing and restoration.

Harvest® PRP is designed to deliver the patient’s own platelets and growth factors at a concentration approximately 4-6 times greater than what is found in regular blood. It delivers a broad range of platelets and growth factors at a concentration that helps optimize healing conditions. In clinical studies, PRP therapy has been shown to help minimize pain, reduce bleeding and infections rates, promote healing, and other positive outcomes.

Here are a few benefits to using this system:

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Recovers the highest percentage of platelets and corresponding growth factors – up to 80% of available platelets
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Contains increased concentrations of stem cells
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Reduces the granulocyte levels to deliver a non-inflammatory product
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Generates the greatest level of reproducibility – only 5% coefficient of variance
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Just 15 minutes processing time for the highest quality PRP

PRP Therapy for Joint Pain FAQs

There is no blood test for the diagnosis of osteoarthritis. Blood tests are performed to exclude diseases that can cause secondary osteoarthritis as well as to eliminate other arthritic conditions that can mimic osteoarthritis.

Separately, certain hormones can assist with the management of inflammation and pain perception. In addition, sex, growth, and thyroid hormones promote the restoration and strength of bone, muscle, and important supporting structures that may aid in the healing of certain injuries. Lab results will be discussed during the procedure and treatments may be offered if any deficiencies are diagnosed.

The majority of PRP patients find that within 3 months of their first treatment, they can return to most or all the activities they were doing before the pain started. Some patients with more difficult injuries may require more than one series of injections to achieve a successful outcome.

We have patients who have reported experiencing significant benefit after a single treatment, while some experienced an increased benefit with 2-3 treatments. Each set of treatments is spaced approximately 12-24 weeks apart. There is no limit to the number of treatments you can have. The risks and side effects do not change with the number of injections.

Kenalog or a similar medication can be used to alleviate any possible pain. This medication can help reduce acute inflammation and pain while the PRP takes effect. A pain injection is optional and administered only without contraindications.

Because PRP effectively induces an inflammatory response, patients will most likely experience some post-procedural pain at the injection site for up to 48 hours. Higher volumes of injected PRP may cause more post-injection pain. Post-procedural pain can typically be managed with ice and over-the-counter pain relievers like acetaminophen.

Non-steroidal anti-inflammatory agents (NSAIDS) such as aspirin (Bayer®) or ibuprofen (Motrin®, Advil®) should be avoided as they exhibit anti-platelet and anti-coagulant effects, which may diminish the effectiveness of the PRP treatment.

PRP Joint Injection Treatment: What’s included?

Blood Work

● Complete Blood Count with differential
● Comprehensive Metabolic Panel-14
● Testosterone Free & Total
● Estradiol
● IGF-1
● Uric Acid

Platelet Evaluation

● Review of X-Rays/Scans and Injury records submitted prior to treatment
● Physical Examination
● Review of Health Questionnaire, blood work, and present symptoms
● Confirmation of PRP treatment and treatment recommendations
● Adjunctive treatment recommendation