Testosterone is available at compounding pharmacies who specialize in hormone preparations.
Compounding pharmacies have the ability customize topically applied testosterone into different strengths and combinations using a variety of transdermal delivery systems (Lipoderm, HRT, Versabase, alcohol gel).
Compounding pharmacies can be used to prescribe a higher concentrated transdermal testosterone which will allow enough of the hormone to be absorbed to maintain a good physiologic level of total testosterone.
In addition, testosterone can be compounded using a custom delivery system which will result in minimal skin reactions. Lipoderm, Versabase, and HRT base are delivery systems that can provide maximum bioavailability and penetration of active ingredients while minimizing skin irritation that can occur with alcohol-based gels or transdermal patches.
The higher dose compounded testosterone creams containing 5% to 20% testosterone have been available by physician’s prescription from any compounding pharmacy specializing in hormone preparations.
The cost for compounded testosterone creams is less than 1% AndroGel® and less expensive generic alternatives can be compounded by many pharmacists. A low dose dihydrotestosterone, DHT gel, labeled Andactrim™, also from Solvay, has been available in Europe for almost a decade. Doctors who specialize in bio-identical hormone replacement therapy have been using cream and gel delivery of female hormones for decades.
Compounded testosterone creams create more physiologic testosterone levels, skin reactions are minimal, and short-term discontinuation of therapy is possible due to the longer half-life of up to 25 hours.
Scrotal application is also convenient and discrete while theoretically producing more DHT than when applied to other locations on the body.