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Ketamine Therapy in Tampa



IV Infusions


Ketamine in Tampa

Ketamine Therapy in Tampa

Break Free From Depression, Stress and PTSD with Ketamine Therapy.

You don’t have to just live with debilitating mental illness symptoms. If you’ve tried other treatments that failed to deliver real results, Ketamine Therapy is an innovative new option to consider. Defy Medical offers this treatment in Tampa, FL, on-site at our clinic.

Ketamine Therapy has shown promise in alleviating symptoms of treatment-resistant conditions like depression, PTSD, and chronic pain. Patients report that this type of therapy has helped ease life-derailing conditions, so they can regain their sense of happiness, drive, and excitement for life.

Email [email protected] to learn more and book an appointment for Ketamine Therapy.  

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Note: While Ketamine has received FDA approval as a safe and effective anesthetic, using the medication to treat mental illness and other conditions is considered an off-label use. Ketamine Therapy does not guarantee results, and each patient may respond differently to the treatment. Consult with a Defy Medical provider to find out if this therapy is right for you.

The Benefits of Ketamine Therapy
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While Ketamine has been used as an anesthetic for over 50 years, recent research illuminates exciting new uses for Ketamine.

Ketamine often produces quicker and more effective results than standard mental health treatments like antidepressants. Ketamine treatment can begin working immediately and some patients report positive effects within minutes of their first treatment (responses vary depending on the individual patient). 

Ketamine has been shown to restore brain function by triggering the brain to grow new synaptic connections in a process called synaptogenesis. These new connections can help address mental disorders and other serious conditions that significantly impact your quality of life.

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Ketamine Therapy can be used to treat:

Treatment-Resistant Depression – This type of depression does not respond to common depression medications like antidepressants. Treatment-resistant depression can have severe negative effects and create a situation that feels hopeless. Recent research suggests that as many as 70% of patients with treatment-resistant depression experienced rapid relief with low-dose Ketamine treatment. This therapy can change the lives of people who believed their depression was untreatable.

Post-Traumatic Stress Disorder – New research supports Ketamine Therapy as a treatment for PTSD in returning combat veterans and others with PTSD symptoms. The degree of relief can vary among patients.

Anxiety Disorders – Ketamine has shown promise in treating anxiety-related mental disorders to improve quality of life and ease severe symptoms. 

Chronic Pain – Ketamine has shown to be effective in treating chronic pain disorders, particularly those that have a neurological component. These include fibromyalgia, complex regional pain syndrome (CRPS), phantom limb pain, and ischemic limb pain.

Improving Brain Function — Ketamine treatment has shown success in improving brain function, including cognition and memory.

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“I was surprised. Of course I wanted it to work, but I’m a bit of a pessimist, so I went into it without much expectation. But I feel a level of calmness that I’ve never really felt. The effects just really decreased my amount of general anxiety after one session.”

—Nina, Defy Medical Ketamine Therapy patient, 
Read Nina's Story 

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Wondering if Ketamine Therapy is right for you? Listen to Nicole Bruce, Vice President of Defy Medical, go over the benefits of Ketamine Therapy on Tampa Bay's Morning Blend.

Watch the short video to learn more about this innovative new treatment for depression, anxiety, and other conditions. 

Our Ketamine Therapy Protocol

We perform our Ketamine IV infusions in Tampa on-site at our clinic. An experienced practitioner will monitor you as you receive your IV dose of Ketamine, which can last for 40 minutes to one hour. We have a specialized room designed to help you stay comfortable and relaxed throughout your treatment.

During your Ketamine treatment, your mind is active while your body relaxes. At low intravenous (IV) doses, Ketamine typically causes deep body relaxation combined with continuous pleasant thoughts, feelings of euphoria and floating, and occasional dizziness.

What to expect during and after your therapy:

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1. Consult with a Defy Medical provider. Before starting treatment, you'll consult with an experienced provider to discuss your condition, goals for treatment, overall health, any medications you're taking, and other factors to make sure Ketamine is a safe treatment for you. You will have an opportunity to ask questions and learn more about Ketamine IV therapy in this consultation.


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2. A relaxing environment to begin your Ketamine treatment. A Defy Medical provider will help you prepare for session in our specialized therapy room. You will sit in a soft, comfortable reclining chair and be provided with an eye mask and headphones that play relaxing music (you can also bring your own headphones if you prefer). Your Ketamine IV infusion will typically last 40 minutes to an hour.


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3. Your Ketamine Therapy experience. Many patients have stream-of-consciousness thoughts during their Ketamine IV infusion. These are usually pleasant and flow gently from one to the other. If you don't experience active thoughts or feelings of lightness and euphoria, that doesn't mean the treatment isn't working. Even if you have a more “normal” experience, Ketamine is likely still building new synaptic connections in your brain, which is what causes the many positive effects. 


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4. The end of your Ketamine IV infusion. Your senses will start to resume within minutes of your Ketamine session ending. Most patients are ready to leave within twenty minutes. We require you to have a family or friend with you to drive you home, since lingering dizziness, lightheadedness, and fatigue can remain for a period of time after treatment. We do not recommend driving until the day after your session, once you’ve had a full night of sleep.


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5. Follow-Up Treatments. The number of required sessions varies from patient to patient. All treatments are customized and tailored to each individual's symptoms and goals. Your practitioner will discuss this with you during your initial evaluation and create a treatment plan that suits your needs. The therapy duration may vary depending on the outcome of the initial intake and medical evaluation.


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Is Ketamine Therapy Covered by Insurance?

Because this is an emerging off-label treatment, Ketamine IV therapy is typically not covered by most insurance. 

Most health insurance companies do not recognize our style of practice, nor do they adequately reimburse for the type of care we provide. Defy Medical strives to provide both quality concierge medical care along with affordable access to compounded medications, blood tests, and nutritional supplements.

In order to accomplish this, we do not accept any form of insurance. Many of the formulations we use in our therapies are not covered by insurance, although the cost of overall treatment is often less than when using insurance.

We are able to provide documentation (for a small administrative fee) which patients can submit to their insurer for potential coverage.   

Frequently Asked Questions about Ketamine

Here are the answers to some commonly asked questions about Defy Medical's Ketamine IV infusion treatment in Tampa, FL. 

Ketamine is a very common anesthetic with a good safety profile. If you’ve ever had a surgery that required anesthesia, your provider likely utilized Ketamine.

However, recent research has shown uses for Ketamine beyond anesthesia.

Ketamine can positively affect the brain by triggering the creation of new synapses between neurons in a process called synaptogenesis. In this way, Ketamine can actually improve the way information travels through the brain – which can help treat serious mental illnesses like depression and PTSD.

Ketamine Therapy is a newly emerging therapy that utilizes Ketamine’s ability to stimulate brain function.

In this type of therapy, the Ketamine doses are much lower, so that the patient doesn’t lose consciousness. Instead, patients typically experience deep body relaxation combined with active, free-flowing thoughts. During the ketamine IV infusion, Ketamine begins working to build new connections in the brain.

Because Ketamine can have immediate effects on the brain, Ketamine Therapy typically provides much quicker results than other mental health treatments like antidepressant medications. Ketamine Therapy typically starts working almost immediately – sometimes even within minutes (though every patient responds differently). Comparatively, antidepressants can take 4 to 8 weeks to begin functioning, and may be less effective with more severe side effects.

Ketamine has also shown success in treating cases of treatment-resistant depression, where medications had little effect.  

Ketamine triggers a process called synaptogenesis, or the creation of new synaptic connections between neurons in the brain. It does this by increasing the activity of a specific neurotransmitter called glutamate, which in turn stimulates the creation of new synapses.

This process can help significantly ease depression and other mental illness symptoms.

Antidepressant medications perform essentially the same function, but they first act on serotonin levels. Serotonin is a neurotransmitter that is responsible for stabilizing mood and sparking happiness, among other functions. Increasing serotonin ultimately increases the activity of glutamate, but it takes much longer to reach the same effect – usually two to four weeks but sometimes more. Because Ketamine affects glutamate directly, the results are more instantaneous. Ketamine has also been effective in treating depression that is resistant to antidepressant medication and other traditional treatments. 

In addition, Ketamine blocks a receptor called N-methyl-D-aspartate (NMDA), which leads to some of the initial depression relief. A metabolized version of Ketamine can stay in the system and extend the effect.

Yes. Ketamine treatment typically works well alongside other mental health therapies. In fact, pairing Ketamine treatment with mental health counseling and other treatments can produce better results than any one therapy alone. Prior to your treatment, your Defy Medical provider will go over any medications you're taking to make sure they won't interfere with the treatment. Ketamine Therapy is typically an ideal option because it is considered to be very safe and effective for most patients. 

Ketamine treatment has an excellent safety profile. However, it is recommended that people with the following health conditions avoid Ketamine treatment:

  • Certain heart or cardiovascular conditions
  • Liver disease
  • Substance abuse disorders
  • Certain psychotic disorders, including a history of drug abuse or dependency on Ketamine
  • Pregnant and breast-feeding mothers
  • High blood pressure — though patients with hypertension may be considered for treatment on a case-by-case basis
  • People with a history of benzodiazepine abuse or a legitimate long-term benzodiazepine protocol may find Ketamine Therapy to be less effective. Sometimes coming off of the medication can improve the therapy's effects. 

Speak with Defy Medical directly to discuss your situation and see if Ketamine IV infusions may work for you. Every patient is different, so an individualized approach is best. 


Before your treatment, a Defy Medical provider will have an in-depth consultation with you to go over your health history, goals for treatment, the condition you're seeking to treat, and more. Your provider will review any medications you're taking to make sure the therapy is as safe and effective as possible for you. Your provider may advise you to pause taking medications or supplements that could interfere with your Ketamine IV infusion, depending on your individual situation. 

To get the most out of this consult, we recommend researching Ketamine treatment beforehand and coming prepared with any questions you wish to ask. You can discuss any concerns, as well, so that you feel confident and informed moving forward. 

Ketamine is given through intravenous (IV) treatments. The number of treatments is based on your individual needs and the condition you're seeking to treat. During the therapy session, you will be seated in a comfortable reclining chair with an eye mask and headphones that play calming music. If you experience nausea, a supplemental medication can easily be added to your IV to help ease this side effect. 

A standard Ketamine IV session usually lasts 40 minutes to one hour. You may experience dizziness and lightheadedness after the treatment, which should begin to dissipate within 15 minutes (though could last as long as a a few hours). We require you to have someone to drive you home, and we do not recommend driving again until you have received a good night's sleep. 

Ketamine Therapy is individualized based on your needs. Your Defy Medical provider will discuss with you your unique situation and decide on a therapy protocol based on your goals. Research shows that weekly to monthly Ketamine treatments can significantly impact treatment-resistant depression and other conditions. 

Ketamine Therapy is an innovative new treatment that shows promise in treating serious and life-interrupting conditions.

However, like most treatments, it works best when paired with lifestyle changes and other mental health therapies. Here are some other things you can incorporate into your treatment plan:

  • Counseling and talk therapy
  • Steady sleep
  • Healthy eating
  • Exercise
  • Meditation and mindfulness

You can also consider hormone optimization if appropriate. Hormonal imbalance can lead to symptoms of depression and mood swings, along with sleeplessness. If you already experience these symptoms, a hormone deficiency can make them more pronounced. Living with chronic stress can also affect hormone levels and push your body out of balance.

Hormone optimization through Testosterone Replacement Therapy and Biodientical Hormone Replacement Therapy can complement Ketamine treatment and increase the chances of long-term success.

Ketamine Therapy is considered safe and effective when administered by trained medical providers.

As with any therapy, though, there are risks and potential side effects. These include: fast heartbeat, increased blood pressure, clear dreams that may seem real, confusion, irritability, floating sensation, feeling “out-of-body,” breathing problems, coughing, nausea, vomiting, muscle twitching, muscle jerks, muscle tension, increased saliva (spit), increased thirst, headaches, metallic taste, constipation, and blurry or double vision. Rare side effects include: allergic reactions, skin rash or pain at the infusion site, euphoria (a feeling of extreme happiness), and involuntary eye movements.

If you experience nausea or motion sickness often, let your provider know so that they can administer an anti-nausea medication along with your IV Ketamine treatment. 

Most side effects dissipate around 15 minutes after the IV infusion ends. 


Ketamine is approved by the FDA as an anesthetic. However, the treatment of conditions like depression and PTSD with Ketamine is considered an "off-label" use. Because of this, insurance companies usually don't cover the treatment.

Defy Medical is a concierge clinic that provides competitively priced therapies at fixed prices. Once you come up with an individualized treatment plant with your provider, you will know how much your treatment costs, and you won't experience any insurance-driven surprises.