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The Benefits of Sermorelin Injections

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A man and woman perform lunges to demonstrate the benefits of Sermorelin injections.

What is Sermorelin?

Sermorelin is an FDA-approved secretagogue that stimulates the pituitary gland to release Human Growth Hormone (hGH).

Sermorelin injections can be used in Growth Hormone Replacement Therapy (GHRT), to optimize hGH levels in the body. This treatment is also called hGH Peptide Therapy.

Read on to learn about the importance of hGH and the potential benefits of GHRT with Sermorelin injections.

What is Human Growth Hormone?

Human Growth Hormone (hGH) is crucial to growth and development.

It controls functions like:

  • Bone, cartilage, and body growth during adolescence
  • Healing and recovery
  • Regulating fat, tissue, muscle, and body composition
  • Cell regeneration and reproduction
  • Regulating metabolism

HGH levels are highest in our youth, while we’re still developing. Levels decreases as we get older, leading to symptoms often associated with aging. These include slower healing, difficulty recovering from exercise, fatigue and insomnia, changes in body fat and composition, and more.

By the time adults reach 55, HCG levels are typically one-tenth of the levels from their youth. This type of aging is sometimes called sarcopenia.

The Effect of Lower hGH Levels

Why does less hGH affect us so much? Since hGH is responsible for healing, recovery, and cell generation, it plays a large factor in aging.

When we’re in our early twenties, our bodies typically generate a new cell for each one that dies. When we reach our fifties, we only regenerate an average of one new cell for every two that die. By the time we turn 70, only one cell is replaced for every three to four that die.

Cell death is a natural process, and it can also be caused by injury and chronic conditions. Since our bodies don’t repair themselves and replace those cells as well when we grow older, we see symptoms of aging like:

  • Appearing to shrink and/or losing height
  • Difficult healing from injury, exercise, and surgery
  • Less muscle growth
  • Delicate bones
  • More frequent injuries
  • Cognitive decline

Sermorelin injections have shown promise in encouraging the production of hGH to ease these symptoms.

A woman looks pensive without smiling as she contemplates the benefits of Sermorelin injections.

Sermorelin Acetate and Growth Hormone Releasing Hormone

Sermorelin Acetate performs the same function as Growth Hormone Releasing Hormone (GHRH). GHRH is produced by the hypothalamus and is responsible for triggering the release of hGH. By causing a similar effect, Sermorelin is useful in elevating hGH levels.

Sermorelin is available as an injection. It’s typically a subcutaneous injection, though your provider may recommend an intramuscular injection depending on your dosage and needs.

There are several over-the-counter supplements that claim to elevate hGH levels in the same way as Sermorelin. In reality, most of these do not substantially affect hGH levels.

If you’re considering a treatment to increase hGH, Peptide Therapy with Sermorelin is typically the most effective way.

Benefits of Sermorelin Injections

Studies have shown that Sermorelin and hGH Peptide Therapy have several benefits.

Improved brain function and alleviated mood disorders.

Sermorelin-stimulated hGH production seems to have a positive effect on the brain. Improved brain function has been observed shortly after administration of Sermorelin injections.

The tie between hGH and mental function has been established. In a study of patients who produced little to no hGH, providers saw decreased brain function, lowered work capacity, depression, self-isolation, mood swings, and anxiety. Study participants also struggled with retaining information, short-term and long-term memory, and motor skills like hand-eye coordination. 1

Another study reported that depressed men release much less hGH during the first three hours of sleep compared to non-depressed study participants. Sleep is the primary time when the body releases hGH.2

These studies, in addition to reports from men and women who experience benefits after increasing their hGH levels using Sermorelin injections, demonstrate that increased hGH affects the human brain in a positive way.

Easing the side effects of aging.

As we age and our hormone levels decrease, many patients find that Sermorelin injections alleviate aging symptoms.

Reported benefits include:

  • Sleeping better and having more energy
  • Improved body composition, with less fat and more muscle
  • Faster healing and recovery after exercise, injury, and/or surgery
  • Improved cognition and better memory
  • Elevated mood and relief from depression


Peptide Therapy with Defy Medical

Defy Medical offers access to hGH Peptide Therapy and Sermorelin injections (as appropriate for the patient).

Many patients have benefited and reported relief from symptoms often associated with aging.

Defy Medical also offers other integrative wellness services, including hormone restoration, fat loss and weight management, nutrition and supplementation, sexual health therapies, and more.

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  1. Klatz, Dr. Ronald; Goldman, Dr. Robert; Stopping the Clock 2003.
  2. P N Sakkas 1, C R Soldatos, J D Bergiannaki, T J Paparrigopoulos, C N Stefanis. Growth hormone secretion during sleep in male depressed patients. Prog Neuropsychopharmacol Biol Psychiatry. 1998 Apr;22(3):467-83. doi: 10.1016/s0278-5846(98)00018-9.