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Medication and Injection Instructions for Sermorelin

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Sermorelin Acetate is used to increase production of Human Growth Hormone (hGH).

Sermorelin comes in lyophilized form, or freeze-dried, and needs to be reconstituted with bacteriostatic water prior to injection.

We’ll walk you through how to mix your Sermorelin and inject it correctly, along with other important details about the medication.

How to Mix Sermorelin

Prior to injecting your medication, you must reconstitute it with bacteriostatic water. Here are step-by-step instructions to mix your Sermorelin.

Step 1: Collect and prep your materials.

Before touching your materials, wash your hands to avoid contamination.

Once that’s done, gather your:

  • Sermorelin Acetate vial
  • Bacteriostatic water vial
  • Alcohol wipes
  • A needle and syringe for reconstituting your Sermorelin (this needle will be disposed of once you’re finished)

Wipe the top of each vial with the alcohol wipe to sterilize them.

Step 2: Draw bacteriostatic water into your syringe.

The amount of bacteriostatic water you need depends on the amount of medication in your vial. The mixing syringe is typically between 3ML and 10ML in size (it’s larger than the injection syringe).

Some general numbers are as follows:

  • 6 mg vial of Sermorelin — Mix in 3 ml of bacteriostatic water
  • 9 mg of Sermorelin — Mix in 5 ml of bacteriostatic water
  • 15 mg vial of Sermorelin — Mix in 7.5 ml of bacteriostatic water

Your provider should give you precise instructions based on your Sermorelin protocol and prescribed dosage. Follow all instructions from your prescriber and/or pharmacy.

Step 3: Inject the bacteriostatic water into the Sermorelin vial.

To prep the syringe, draw in air to the appropriate measurement on the syringe. Then hold the vial of bacteriostatic water upside down and push the needle through the stopper.

Inject the air into the vial slowly, adjusting if you feel pressure. Once the air is injected, the bacteriostatic water should begin flowing into the syringe. Remove the needle from the stopper once you have reached the desired amount.

Avoid touching the needle to anything else as you pick up your Sermorelin vial. Pierce the stopper of the medication vial, and inject the bacteriostatic water into your lyophilized Sermorelin. Go slowly, and pause if you feel any resistance.

Step 4: Mix your Sermorelin.

Gently swirl the solution to combine the bacteriostatic water and lyophilized Sermorelin. Do not shake aggressively. Continue swirling until the powder is fully dissolved.

Your mixed medication should last up to 90 days, and it should be refrigerated after reconstitution.

Sermorelin can maintain its effectiveness when it’s left out of the fridge for under 72 hours. If you accidentally leave it out for longer, you should reach out to your prescriber and pharmacy to replace the vial.

Place your mixing needle and syringe into a Sharps container for safe disposal.

How to Inject Sermorelin

Once you’ve reconstituted your Sermorelin, it’s time to inject. Follow these instructions to self-administer your medication.

Step 1: Prep your syringe and draw your medication.

Sermorelin is typically injected with a small insulin needle. Your provider should offer guidance and access to the necessary materials, so you have everything you need.

Ten units on the syringe equals 200 mcg of Sermorelin. How much you inject depends on your prescribed dosage.

  • If you’re prescribed 1 mg (1000 mcg), you would draw the medication to the 50 unit mark.
  • If you’re prescribed 0.5 mg (500 mcg), you would draw up to the 25 unit mark.

Prepare your injection needle and clean the rubber stopper of your medication vial with an alcohol wipe. Then pull air into your injection needle to the appropriate mark for your dosage.

Flip your medication vial upside down and pierce the stopper. Slowly and carefully inject air into the vial, and allow the medication to fill the syringe to the appropriate amount.

Step 2: Inject Your Sermorelin

Sermorelin is a subcutaneous injection, which means it’s injected into the fatty layer of the skin.

Subcutaneous injections can be administered to multiple places, including:

  • Upper arms
  • Abdomen
  • Thighs
  • Buttocks

Rotate your injection sites regularly to avoid fatigue and soreness.

When you’re ready to inject, wipe your chosen injection spot with an alcohol wipe to sterilize it.

Then pinch your skin between two fingers and hold the needle at a 45- or 90-degree angle depending on the injection site. Inject your medication slowly and carefully; do not press the plunger aggressively or inject the medication quickly.

Learn more about how to perform subcutaneous injections.

Be sure to properly dispose of all syringes and needles in your Sharps container after use.

Common Uses for Sermorelin

Sermorelin can treat two types of hGH deficiencies:

  • Adult Onset: This includes patients who have growth hormone deficiency either alone, or associated with other hormone deficiencies (hypopituitarism), as a result of pituitary disease, hypothalamic disease, surgery, radiation therapy, trauma, or aging.
  • Childhood Onset: This includes patients who experience a deficiency in hGH in their childhood and adolescence. This condition is sometimes diagnosed as an adult.

What to Know Before Using Sermorelin

  • Use this medication exactly as prescribed and follow your provider’s instructions.
  • Bacteriostatic water includes 0.9% Benzyl Alcohol to ensure the water is sterilized. Do not use any other diluent unless instructed by your prescribing physician.
  • Prior to using Sermorelin, inform your provider if you’re allergic to any prescription or non-prescription medicine, taking other medicines or have other medical problems, are pregnant, are planning a pregnancy, or are breast feeding.
  • If your medication is cloudy or contains particles, do not inject. Contact your provider and/or the pharmacy. Defy Medical patients can contact the Patient Care team for guidance at [email protected].
  • If you miss a dose, inject your Sermorelin when you remember, but do not double dose. If it’s already time for your next injection, simply inject your standard dose.
  • Refrigerate your Sermorelin medication in its original vial away from children. Do not freeze your Sermorelin, and discard any unused medicine.

Potential Adverse Reactions

Sermorelin is well tolerated by most individuals, but there are potential side effects. These side effects are arranged from most common to least common:

  • Warmth and/or flushing of the face
  • Injection site pain Redness and/or swelling at injection site
  • Nausea
  • Headache
  • Vomiting
  • Strange taste in the mouth
  • Paleness
  • Tightness in the chest

Rarely, patients may experience more serious side effects. Discuss potential side effects with your provider prior to beginning your Sermorelin protocol.

Sermorelin at Defy Medical

Defy Medical offers Sermorelin Peptide Therapy for qualifying patients. This therapy encourages the production of hGH to ease symptoms that are often considered part of aging.

It’s important to mix and inject Sermorelin correctly to ensure best results. Defy Medical offers one-on-one guidance through our Patient Support Team and in-depth consultations with experienced providers.

Not yet on a Sermorelin protocol?

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