Progesterone is an essential raw material from which your body makes many of the other hormones vital for good health.

Symptoms Associated with Progesterone Deficiency


  • Fibrocystic breasts or breast pain
  • Anxiety
  • Fluid Retention
  • Stressed Easily
  • Weight gain
  • Irritability
  • Break-through-bleeding
  • PMS
  • Low Body Temperature
  • Hair Loss
  • Headaches/migraines
  • Endometriosis
  • Sleep Disturbances
  • Heavy Periods
  • Cramps
  • Fibroids
  • Hypothyroidism
  • Bone Loss
  • Irregular cycle/spotting between cycles
  • Infertility


  • Anxiety
  • Over Reacting
  • Easily alarmed
  • Stressed
  • Feelings of confusion
  • Mood swings
  • Irritability
  • Nervous
  • Jittery
  • Depression

Why is Progesterone important to supplement when deficient?

Roles and Properties of Progesterone

  • Decreases menstrual bleeding
  • Decreases fat storage
  • Anti-cancer; especially protective of the breast
  • Increases body supply of oxygen
  • Helps prevent hardening of the arteries
  • Improves brain structure and function, memory
  • Increases metabolic rate
  • Helps regulate water retention
  • Required for conception and gestation
  • Increases intelligence of fetus
  • Mild sedative in large doses
  • Protects against miscarriage
  • Prevents PMS
  • Stimulates new bone formation
  • Anti-aging to skin
  • Inhibits Fibrocystic Breast Disease
  • Natural antidepressant
  • Facilitates thyroid hormone action
  • Normalizes blood sugar levels
  • Reduces spotting
  • Tones blood vessels
  • Reduces irritability and anxiety
  • Reduces testosterone imbalance
  • Prevents endometrial cancer
  • Anti-aging hormone
  • Useful in some cases of seizure disorder
  • Helps prevent high blood pressure
  • Reduces risk of autoimmune diseases
  • Increases (Ig-E) to help prevent sinus, respiratory, vaginal infections and allergic reactions
  • Increases sensitivity of estrogen receptors
  • Natural diuretic
  • Raises HDL, lowers triglycerides
  • Restores sex drive
  • Functions as a precursor to corticosteriods and other steroidal hormones
  • Blocks estrogen's side effects and excessive estrogen
  • Increases endurance during exercise
  • Calms and protects nervous system
  • Protective effect on brain chemistry
  • Reduces cravings for sweets/carbs
  • Thymus gland depends on progesterone
  • Most protective hormone the body produces
  • Improve efficiency of the heart
  • Basic hormone of adaptation and resistance to stress
  • Restores normal sleep patterns
  • Enhances number of insulin receptors on cells
  • Used by adrenals to produce anti-stress hormones

In addition, Progesterone has many clinical benefits to both women and men. Progesterone can be used to treat fibroids, Traumatic Brain Injuries (TBI), Post Natal Psychosis, and neuropathy.

A simple blood test and review of your symptoms will determine if you can benefit from progesterone restoration. Defy Medical uses only Bio-Identical Progesterone which is prescribed through a licensed US compounding pharmacy. Progesterone can be compounded into capsules,topical creams, or sublingual troches or drops.




Defy Medical strives to provide both quality medical care along with affordable access to compounded medications, blood tests, and nutritional supplements. In order to accomplish this, Defy Medical does not accept any form of insurance. Many of the formulations we use in our therapies are not covered by insurance, and the cost of overall treatment is often less than when using insurance. On case by case basis, some insurance companies do reimburse for Hormone Replacement Therapy and Testosterone Replacement Therapy. It is each patient's responsibility to contact their own insurance company to confirm reimbursement. Defy Medical will not contact your insurance company nor will take any responsibility for any additional forms your insurance requires. Defy Medical provides claim assistance by completing the standard claim form (CMS-1500) for the patient to submit to their insurance company. If you would like to receive Claim Assistance, please contact patient services at