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Find the root cause of your symptoms with Defy Medical.

"Why do I feel this way?"

Feeling a decline in drive, energy, and libido? Defy Medical uses in-depth consultations, comprehensive blood testing, and a decade of experience to develop customized treatments via telemedicine.

Feel better. Defy expectations.

Defy Medical

The World’s Leading Hormone Replacement Clinic

Defy Medical has guided thousands of patients to living healthier, happier lives – and we’re ready to help you. Our experienced care team specializes in hormone restoration and integrative therapies designed to help you feel better.

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Wondering if HRT is right for you?

Take our 3-minute quiz to see if you may be a candidate for Hormone Replacement Therapy.

This quiz is meant to provide guidance and is not intended to be medical advice. Blood testing and consulting with a knowledgeable provider are required to diagnose hormone deficiency.

Take the Quiz

Some of Our

Core Services

For Men

Learn MoreA man smiles as he runs near a bridge and body of water, showing the benefits of Testosterone Replacement Therapy online.

Testosterone Replacement Therapy

Optimize your levels and performance with a customized treatment plan for low Testosterone (hypogonadism).

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Learn MoreA black man hugs his partner, a black woman, as they smile because they successfully treated erectile dysfunction (ED).

Erectile Dysfunction

Regain satisfaction with your sex life and enhance your sexual performance. Find effective and affordable therapies for erectile dysfunction.

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For Women

Learn MoreA mature woman sits on a couch smiling in a yellow sweater, showing the success of her hormone therapy.

Hormone Therapy

Combat the effects of hormone imbalance and regain your zest for life with Bioidentical Hormone Replacement Therapy (BHRT).

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Learn MoreA man and woman smile at the camera as the woman hugs the man from behind, celebrating their treatment of female sexual dysfunction.

Sexual Dysfunction

Enhance intimacy with treatments designed to boost libido, improve sensation, and ease pain during intercourse.

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Meet our Care Team

Led by Medical Director Dr. Justin Saya, our care team has extensive experience in hormone restoration, sexual health treatment, and integrative wellness. They’re passionate about helping patients improve their lives and feel their best.

See Our Providers

What Our Patients are Saying

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“Working with Defy has been the best decision I've ever made...”

Dr. Saya and team have been a godsend for me. Other doctors have brushed me off, saying my labs were in ‘normal’ range, but never listened to the symptoms I was suffering from. Working with Defy has been the best decision I’ve ever made, and I’ll continue to recommend them to others.

–Mike

“I no longer have the hot flashes (YES!), and my moods are even...”

[My husband and I] have been seeing Dr. Saya, and now Jill, for several years now. I even switched my thyroid care to them as well. I no longer have the hot flashes (YES!), and my moods are even, no extreme mood swings. Thank goodness!

–Kimberly

“I want to thank Dr. Calkins from the bottom of my heart.”

No doctor in my town wanted to treat me because I was only 25, despite having diagnosis, imaging and bloodwork indicating I needed the help. I want to thank Dr. Calkins from the bottom of my heart. The past few months have been so liberating for me and I finally feel in control of my life. Also, for the first time in my life, I can truly say I’m happy. I’m not just going through the motions to get through the day anymore.

–Alan